What blood group does diabetes have

Diabetes: Lowest risk with blood group 0

Villejuif (France) - The likelihood of developing type 2 diabetes also depends on the blood type. People with blood group 0 have the lowest risk of disease, and those with blood group B are the greatest. This is the result of the largest predictive study of this kind to date, in which only women took part. French researchers report in the journal “Diabetologia”, however, that the connections are very likely also transferable to men. How the blood group could influence the development of the metabolic disease is not yet known.

"The importance of the different blood groups for diabetes should be explored in future clinical and epidemiological studies," says Guy Fagherazzi from the Gustave-Roussy Institute in Villejuif. His research team evaluated data from 82,104 participants in a long-term study started in 1990. Six years after the start, blood sugar and fat levels were also determined in a sample of 800 women. Compared to women with blood group 0, the risk of diabetes with blood group A was increased by 10 percent and with blood group B by as much as 21 percent. The group of all rhesus factor-positive women did not differ from the rhesus factor-negative women in terms of risk of disease. The comparison between people with different combinations of rhesus factor and blood groups of the AB0 system showed: Those with blood group B, rhesus-positive were 35 percent more likely to develop diabetes than women with blood group 0, rhesus-negative. These statistical relationships persisted in the sample even if the blood sugar level and fat values ​​were taken into account.

In contrast to those with blood group 0, people with blood group A, B or AB form certain proteins or lipids on the surface of the red blood cells. The authors suspect that these could increase the production of inflammatory messenger substances. That would encourage the development of diabetes. But there are also other explanations. So it would be possible that the individual blood groups have different effects on the composition of the intestinal flora. And the intestinal germs are known to influence inflammatory reactions in the body as well as the regulation of energy balance and sugar metabolism.

© Wissenschaft aktuell